No, they are not pre-drilled. This way you can attach any of our handles to your doors. The handles' shape and size determine where they will look best on the door.
To know where your particular handle is best placed, see our recommendation that comes with the assembly instructions. If you want to drill a hole for the handle yourself, place a piece of wood on the backside of the door as you drill. This way the drill has something to drill into when it passes through the wood, and wood tear-out is minimized.
Handle mounting instructions: